The Radisic Lab

“Cardiac Tissue Engineering Methods and Protocols” edited by Milica Radisic and Lauren Black, Humana Press/Springer Protocols in the series “Methods in Molecular Biology”, 2014: https://www.springer.com/gp/book/9781493910465

250) Lutolf MP, Radisic M, Beekman J, Huh DD, Huch M, Turco MY, Tahmasebi Birgani ZN, Gao D, Yao R, Lin H, Takebe T. In vitro human cell-based models: What can they do and what are their limitations? Cell. 2024 Aug 22;187(17):4439-4443. doi: 10.1016/j.cell.2024.07.042. PMID: 39178827.

249) Wagner, K. T., Lu, R. X., Landau, S., Shawky, S. A., Zhao, Y., Bodenstein, D. F., Jiménez Vargas, L. F., Jiang, R., Okhovatian, S., Wang, Y., Liu, C., Vosoughi, D., Gustafson, D., Fish, J. E., Cummins, C. L., & Radisic, M. (2024). Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues. Biofabrication, 16(4), 045037. https://doi.org/10.1088/1758-5090/ad76d9

248) Radisic, M., & Kaplan, D. L. (2024). Serving a diverse biomaterials community for 10 years. ACS Biomaterials Science & Engineering, 10(9), 5409–5411. https://doi.org/10.1021/acsbiomaterials.4c01355

247) Bannerman, D., Pascual-Gil, S., Wu, Q., Fernandes, I., Zhao, Y., Wagner, K.T., Okhovatian, S., Landau, S., Rafatian, N., Bodenstein, D.F., Wang, Y., Nash, T.R., Vunjak-Novakovic, G., Keller, G., Epelman, S. and Radisic, M. (2024), Heart-on-a-Chip Model of Epicardial–Myocardial Interaction in Ischemia Reperfusion Injury (Adv. Healthcare Mater. 21/2024). Adv. Healthcare Mater., 13: 2470133. https://doi.org/10.1002/adhm.202470133

246) Okhovatian, S., Khosravi, R., Wang, E. Y., Zhao, Y., & Radisic, M. (2024). BIOFABRICATION strategies for Cardiac Tissue Engineering. Current Opinion in Biotechnology, 88, 103166. https://doi.org/10.1016/j.copbio.2024.103166

245) Wu, Q., Rafatian, N., Wagner, K. T., Blamer, J., Smith, J., Okhovatian, S., Aggarwal, P., Wang, E. Y., Banerjee, A., Zhao, Y., Nash, T. R., Lu, R. X., Portillo-Esquivel, L. E., Li, C. Y., Kuzmanov, U., Mandla, S., Virlee, E., Landau, S., Lai, B. F., … Radisic, M. (2024). SARS-COV-2 pathogenesis in an angiotensin II–induced heart-on-a-chip disease model and extracellular vesicle screening. Proceedings of the National Academy of Sciences, 121(28). https://doi.org/10.1073/pnas.2403581121

244) Zhao, Y., Landau, S., Okhovatian, S. et al. Integrating organoids and organ-on-a-chip devices. Nat Rev Bioeng 2, 588–608 (2024). https://doi.org/10.1038/s44222-024-00207-z

243) Landau, S., Zhao, Y., Hamidzada, H., Kent, G. M., Okhovatian, S., Lu, R. X., Liu, C., Wagner, K. T., Cheung, K., Shawky, S. A., Vosoughi, D., Beroncal, E. L., Fernandes, I., Cummins, C. L., Andreazza, A. C., Keller, G. M., Epelman, S., & Radisic, M. (2024). Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms. Cell Stem Cell, 31(8). https://doi.org/10.1016/j.stem.2024.05.011

242) Bodenstein, D.F., Siebiger, G., Zhao, Y. et al. Bridging the gap between in vitro and in vivo models: a way forward to clinical translation of mitochondrial transplantation in acute disease states. Stem Cell Res Ther 15, 157 (2024). https://doi.org/10.1186/s13287-024-03771-8

241) Ganji, N., Kalish, B., Offringa, M., Li, B., Anderson, J., Baruchel, S., Blakely, M., De Coppi, P., Eaton, S., Gauda, E., Hall, N., Heath, A., Livingston, M. H., McNair, C., Mitchell, R., Patel, K., Pechlivanoglou, P., Pleasants-Terashita, H., Pryor, E., … Pierro, A. (2024). Translating regenerative medicine therapies in neonatal necrotizing enterocolitis. Pediatric Research. https://doi.org/10.1038/s41390-024-03236-x

240) Kinnear C, Said A, Meng G, Zhao Y, Wang EY, Rafatian N, Parmar N, Wei W, Billia F, Simmons CA, Radisic M, Ellis J, Mital S. Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction. Cell Reports Medicine. 2024 May 21; 5(5): 101520. doi: https://doi.org/10.1016/j.xcrm.2024.101520

239) Bannerman D, Pascual S, Wu Q, Fernandes I, Zhao Y, Wagner KT, Sargol Okhovatian, Landau S, Naimeh Raftian, Bodenstein DF, et al. Heart‐on‐a‐Chip Model of Epicardial‐Myocardial Interaction in Ischemia Reperfusion Injury. Advanced Healthcare Materials. 2024 Apr 29. doi: https://doi.org/10.1002/adhm.202302642

238) Karamzadeh V; Shen ML; Ravanbakhsh H; Sohrabi-Kashani A; Okhovatian S; Savoji H; Radisic M; Juncker D; High-resolution additive manufacturing of a biodegradable elastomer with a low-cost LCD 3D printer. Advanced Healthcare Materials. 2024 April 05; 13(9): 2470062. doi: https://doi.org/10.1002/adhm.202470062

237) Wang Y, Vizely K, Li CY, Shen K, Shakeri A, Khosravi R, Smith JR, Alfonzo E, Alteza A, Zhao Y, et al. Biomaterials for immunomodulation in wound healing. Regenerative Biomaterials. 2024 Mar 27. doi:10.1093/rb/rbae032

236) Lu RX, Rafatian N, Zhao Y, Wagner KT, Beroncal EL, Li B, Lee C, Chen J, Churcher E, Vosoughi D, et al. Cardiac tissue model of immune-induced dysfunction reveals the role of free mitochondrial DNA and the therapeutic effects of exosomes. Science Advances. 2024 Mar 27; 10(13). doi:10.1126/sciadv.adk0164

235) Ashrafi E, Radisic M, Elliott JA. Systematic cryopreservation study of cardiac myoblasts in suspension. PLoS One. 2024 March 06; 19(3). doi:10.1371/journal.pone.0295131

234) Wu Q, Xue R, Zhao Y, Ramsay K, Wang EY, Savoji H, Veres T, Cartmell SH, Radisic M. Automated fabrication of a scalable heart-on-a-chip device by 3D printing of thermoplastic elastomer nanocomposite and hot embossing. Bioactive Materials. 2024 March; 33:46–60. doi:10.1016/j.bioactmat.2023.10.019

233) Cho S, Dadson K, Sung HK, Ayansola O, Mirzaesmaeili A, Noskovicova N, Zhao Y, Cheung K, Radisic M, Hinz B, et al. Cardioprotection by the adiponectin receptor agonist ALY688 in a preclinical mouse model of heart failure with reduced ejection fraction. Biomedicine & Pharmacotherapy. 2024 February; 171:116119. doi:10.1016/j.biopha.2023.116119

232) Bannerman D, Pascual-Gil S, Campbell S, Jiang R, Wu Q, Okhovatian S, Wagner KT, Montgomery M, Laflamme MA, Davenport Huyer L, et al. Itaconate and citrate releasing polymer attenuates foreign body response in biofabricated cardiac patches. Materials Today Bio. 2024 February; 24:100917. doi:10.1016/j.mtbio.2023.100917

231) EM, Callaghan NI, Ding Y, Latifi N, Rafatian N, Funakoshi S, Fernandes I, Reitz CJ, Di Paola M, Gramolini AO, et al. Noninvasive quantification of contractile dynamics in cardiac cells, spheroids, and organs-on-a-chip using high-frequency ultrasound. ACS Nano. 2023 December 26; 18(1):314–327. doi:10.1021/acsnano.3c06325

230) Rabiee N, Dokmeci MR, Zarrabi A, Makvandi P, Saeb MR, Karimi-Maleh H, Jafarzadeh S, Karaman C, Yamauchi Y, Warkiani ME, Radisic M, et al. Green biomaterials: Fundamental principles. Green Biomaterials. 2023 December 06; 1(1):1–4. doi:10.1080/29934168.2023.2268943

229) Shakeri A, Wang Y, Zhao Y, Landau S, Perera K, Lee J, Radisic M. Engineering organ-on-a-chip systems for Vascular diseases. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023 Oct 12; 43(12):2241–2255. doi:10.1161/atvbaha.123.318233

228) Radisic M. Hydrogel implant rehabilitates muscles through electrical stimulation. Nature. 2023 November 01; 623(7985):37–38. doi:10.1038/d41586-023-03211-2

227) Kieda J, Shakeri A, Landau S, Wang EY, Zhao Y, Lai BF, Okhovatian S, Wang Y, Jiang R, Radisic M. Advances in cardiac tissue engineering and heart‐on‐a‐chip. Journal of Biomedical Materials Research Part A. 2023 November 01; 112(4):492–511. doi:10.1002/jbm.a.37633

226) Wauchop M, Rafatian N, Zhao Y, Chen W, Gagliardi M, Massé S, Cox BJ, Lai P, Liang T, Landau S, et al. Maturation of ipsc-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation. Biomaterials. 2023 October; 301:122255. doi:10.1016/j.biomaterials.2023.122255

225) Okhovatian S, Shakeri A, Davenport Huyer L, Radisic M. Elastomeric Polyesters in Cardiovascular Tissue Engineering and Organs-on-a-Chip. Biomacromolecules. 2023 Nov 13;24(11):4511-4531. doi: 10.1021/acs.biomac.3c00387. Epub 2023 Aug 28. PMID: 37639715.

224) Lu, RXZ, Zhao, Y, Radisic, M. The emerging role of heart-on-a-chip systems in delineating mechanisms of SARS-CoV-2-induced cardiac dysfunction. Bioeng Transl Med. 2023;e10581. doi:10.1002/btm2.10581

223) Marianne Wauchop, Naimeh Rafatian, Yimu Zhao, Mark Gagliardi, Stéphane Massé, Brian J. Cox, Patrick Lai, Timothy Liang, Shira S. Landau, Stephanie Protze, Xiao Dong Gao, Erika Yan Wang, Kelvin Chan Tung, Zachary Laksman, Rick Lu, Gordon Keller, Kumaraswamy Nanthakumar, Milica Radisic, Peter H. Backx,”Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation”, Biomaterials, 2023, 122255, ISSN 0142-9612,

222) Rick Xing Ze Lu, Naimeh Rafatian, Yimu Zhao, Karl T. Wagner, Erika L. Beroncal, Bo Li, Carol Lee, Jingan Chen, Eryn Churcher, Daniel Vosoughi, Ying Wang, Andrew Baker, Uriel Trahtemberg, Bowen Li, Agostino Pierro, Ana C. Andreazza, Claudia C. dos Santos, Milica Radisic,”Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the role of free mitochondrial DNA and therapeutic effects of endothelial exosomes”, bioRxiv 2023.08.09.552495; doi: https://doi.org/10.1101/2023.08.09.552495.

221) Karamzadeh, Vahid & Shen, Molly & Ravanbakhsh, Hossein & Sohrabi, Ahmad & Savoji, Houman & Radisic, Milica & Juncker, David. (2023). High-Resolution Additive Manufacturing of a Biodegradable Elastomer with a Low-Cost LCD 3D Printer. 10.1101/2023.06.15.545079.  

220) Wu Q, Zhang P, O’Leary G, Zhao Y, Xu Y, Rafatian N, Okhovatian S, Landau S, Valiante TA, Travas-Sejdic J, Radisic M. Flexible 3D printed microwires and 3D microelectrodes for heart-on-a-chip engineering. Biofabrication. 2023 Jun 22;15(3):035023. doi: 10.1088/1758-5090/acd8f4. PMID: 37230083; PMCID: PMC10285507.

219) Yimu Zhao, Erika Yan Wang, Fook B.L. Lai, Krisco Cheung, Milica Radisic, Organs-on-a-chip: a union of tissue engineering and microfabrication, Trends in Biotechnology, Volume 41, Issue 3,2023, Pages 410-424, ISSN 0167-7799, https://doi.org/10.1016/j.tibtech.2022.12.018.

218) Neelkanth M. Bardhan, Milica Radisic, and Md Nurunnabi: “Bioinspired Materials for Wearable Diagnostics and Biosensors”, ACS Biomaterials Science & Engineering 2023 9 (5), 2015-2019, DOI: 10.1021/acsbiomaterials.3c00348

217) Vizely K, Wagner KT, Mandla S, Gustafson D, Fish JE, Radisic M: “Angiopoietin-1 derived peptide hydrogel promotes molecular hallmarks of regeneration and wound healing in dermal fibroblasts” iScience, 26, 105984. DOI: 10.1016/j.isci.2023.105984, 2023

216) Zhao Y, Wang EY, Lai FBL, Cheung K, Radisic M: “Organs-on-a-chip: a union of tissue engineering and microfabrication” Trends in Biotechnology, 41, 410-424. DOI: 10.1016/j.tibtech.2022.12.018, 2023 (featured article in 40th Anniversary Issue)

214) Wang EY, Zhao Y, Okhovatian S, Smith JB, Radisic M: “Intersection of stem cell biology and engineering towards next generation in vitro models of human fibrosis” Frontiers in Bioengieering and Biotechnology, 10, 1005051. DOI: 10.3389/fbioe.2022.1005051, 2022

213) Okhovatian S, Mohammadi MH, Rafatian N, Radisic M: “Engineering Models of the Heart Left Ventricle”, ACS Biomaterials Science & Engineering, 8, 2144-2160. DOI: 10.1021/acsbiomaterials.1c00636, 2022

212) Sparks HD, Mandla S, Vizely K, Rosin N, Radisic M, Biernaskie J: “Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds”, Scientific Reports, 12, 14233. DOI: 10.1038/s41598-022-18204-w, 2022

211) Wang E.Y., Smith J., and Radisic M: “Design and Fabrication of Biological Wires for Cardiac Fibrosis Disease Modeling”, Cardiac Tissue Engineering, 2nd Edition, edited by Lauren Black, III and Kareen Columbe, Methods in Molecular Biology, Springer, June 04th, 2022

210) Liu C, Campbell SB, Li J, Bannerman D, Pascual-Gil S, Kieda J, Wu Q, Herman PR, Radisic M: “High Throughput Omnidirectional Printing of Tubular Microstructures from Elastomeric Polymers” Advanced Healthcare Materials, 11, e2201346. e2201346. doi: 10.1002/adhm.202201346, 2022 (cover article)

209) Mohammadi MH, Okhovatian S, Savoji H, Campbell SB, Lai BFL, Wu J, Pascual-Gil S, Bannerman D, Rafatian N, Li RK, Radisic M: “Hierarchical assembly of aligned cell sheets into a conical cardiac ventricle using microfabricated elastomers” Advanced Biology, 6, e2101165, DOI: 10.1002/adbi.2021011652022, 2022 (cover article)

208) Lu RXZ, Lai BFL, Rafatian N, Gustafson D, Campbell SB, Banerjee A, Kozak R, Mossman K, Mubareka S, Howe KL, Fish JE, Radisic M, “Vasculature-on-a-chip platform with innate immunity enables identification of angiopoietin-1 derived peptide as a therapeutic for SARS-CoV-2 induced inflammation”, Lab-on-a-Chip, 22, 1171-1186, 2022

207) Gustafson D, Ngai M, Wu R, Hou H, Schoffel AC, Erice C, Mandla S, Billia F, Wilson MD, Radisic M, Fan E, Trahtemberg U, Baker A, McIntosh C, Fan CS, Dos Santos CC, Kain KC, Hanneman K, Thavendiranathan P, Fish JE, Howe KL, “Cardiovascular signatures of COVID-19 predict mortality and identify barrier stabilizing therapies”, EBioMedicine, 78, 103982, 2022

206) Okhovatian S, Mohammadi MH, Rafatian N, Radisic M: “Engineering models of the heart left ventricle”ACS Biomaterials Science & Engineering, 2022

205) Wang EY, Smith J, Radisic M: ”Design and Fabrication of Biological Wires for Cardiac Fibrosis Disease Modeling “ book chapter in “Cardiac Tissue Engineering” 2nd Ed by Lauren D Black III and Karen Coulombe, Methods in Molecular Biology, Springer Protocols, June 04th, 2022

204) Knee-Walden EJ, Wagner K, Wu Q, Rafatian N, Radisic M: “Microfabricated Systems for Cardiovascular Tissue Modeling”, Chapter 4. Cardiovascular Tissue Engineering and Biomaterials (II), in Advanced Technologies in Cardiovascular Bioengineering, edited by Jay Zhang and Vahid Serpooshan, Springer, 2022. p. 193-232. (book chapter)

203) Lai BFL, Lu RXZ, Davenport Huyer L, Kakinoki S, Yazbeck J, Wang EY, Wu Q, Zhang B, Radisic M: “A well-plate based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature”, Nature Protocols, 1-32, March, 2021 (featured on Nature Protocols web site)

202) Shou Y, Campbell SB, Davenport Huyer L, Radisic, M: “ Towards renewable and functional biomedical polymers with tunable degradation rates based on itaconic acid: ACS Applied Polymer Materials, March, 2021 (cover article)

201) Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M, “An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy”, Journal of Molecular and Cellular Cardiology, 160, 97-110, 2021

200) Sparks HD, Sigaeva T, Tarraf S, Mandla S, Pope H, Hee O, Di Martino ES, Biernaskie J, Radisic M, Scott WM, “Biomechanics of Wound Healing in an Equine Limb Model: Effect of Location and Treatment with a Peptide-Modified Collagen-Chitosan Hydrogel”, ACS Biomaterials Science & Engineering 7, 265-278, 2021

199) KT Wagner, TR Nash, B Liu, G Vunjak-Novakovic, M Radisic: “Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip” Trends in Biotechnology, https://doi.org/10.1016/j.tibtech.2020.08.005, 39, 755-773, 2021

198) Campbell SB, Wu Q, Yazbeck J, Liu C, Okhovatian S, Radisic M: “Beyond Polydimethylsiloxane: Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems”, ACS Biomaterials Science & Engineering, https://doi.org/10.1021/acsbiomaterials.0c00640, 7, 2880-2899, 2021

197) Lu RXZ, Radisic M: “Organ-on-a-chip platforms for evaluation of environmental nanoparticle toxicity”, Bioactive Materials, 6, 2801-2819, 2021 (Editor’s Gold Open Access)

196) LD Huyer, Radisic M: “An Organ-on-a-Chip System to Study Anaerobic Bacteria in Intestinal Health and Disease”, Med 2, 16-18, 2021

195) Bannerman D, Pascual-Gil S, Floryan M, Radisic M: “Bioengineering strategies to control epithelial-to-mesenchymal transition for studies of cardiac development and disease”, APL Bioengineering, 5, 021504 (2021) (Editor’s choice)

194) Lock R, Al Asafen H, Fleischer S, Tamargo M, Zhao Y, Radisic M, Vunjak-Novakovic G: “A framework for developing sex-specific engineered heart models”, Nature Reviews Materials, 1-19, 2021

193) Vunjak-Novakovic G, Ronaldson-Bouchard K, Radisic M: “Organs on a chip models for biological research”, Cell, 84(18):4597-4611, 2021

192) Wagner KT, Radisic M, “A New Role for Extracellular Vesicles in Cardiac Tissue Engineering and Regenerative Medicine”, Advanced NanoBiomed Res, 1, 2021

191) Radisic M, Loskill P, “Beyond PDMS and Membranes: New Materials for Organ-on-a-Chip Devices”, ACS Biomaterials Science & Engineering, 7, 2861-2863, 2021

190) Rafatian N, Vizely K, Al Asafen H, Korolj A, Radisic M, “Drawing Inspiration from Developmental Biology for Cardiac Tissue Engineers”, Advanced Biology, 5, e2000190, 2021

189) Lu RXZ, Radisic M, “Organ-on-a-chip platforms for evaluation of environmental nanoparticle toxicity”, Bioactive Materials, 6, 2801-2819, 2021

188) Savoji H, Davenport Huyer L, Mohammadi MH, Lun Lai BF, Rafatian N, Bannerman D, Shoaib M, Bobicki ER, Ramachandran AR, Radisic M; “3D Printing of Vascular Tubes Using Bioelastomer Prepolymers by Freeform Reversible Embedding” ACS Biomaterials Science & Engineering, 2020 (cover paper) https://doi.org/10.1021/acsbiomaterials.9b00676

187) Mirani B, Pagan E, Shojaei S, Hossein Dabiri SM, Savoji H, Mehrali M, Sam M, Alsaif J, Bhiladvala RB, Dolatshahi-Pirouz A, Radisic M, Akbari M; “Facile Method for Fabrication of Meter-Long Multifunctional Hydrogel Fibers with Controllable Biophysical and Biochemical Features” ACS Applied Materials & Interfaces, 12, 9080-9089, 2020 (Feb 2020) https://doi.org/10.1021/acsami.9b23063

186) Kinnear C, Agrawal R, Loo C, Pahnke A, Rodrigues DC, Thompson T, Akinrinade O, Ahadian S, Keeley F, Radisic M, Mital S, Ellis J: “Everolimus Rescues the Phenotype of Elastin Insufficiency in Patient Induced Pluripotent Stem Cell–Derived Vascular Smooth Muscle Cells”, Arteriosclerosis, Thrombosis, and Vascular Biology, 40, 1325-1339, 2020

185) Xie R, Korolj A, Liu C, Song X, Lu RXZ, Zhang B, Liang Q, Radisic M: “h-FIBER: Microfluidic topographical hollow fiber for studies of glomerular filtration barrier” ACS Central Science, 2020, https://doi.org/10.1021/acscentsci.9b01097 (cover paper)

184) Savoji H, Davenport-Huyer L, Mohammadi MH, Lai BF, Bannerman D, Shoaib M, Bobicki ER, Radisic M: “3D printing of microvasculature using bioelastomer prepolymers by freeform reversible embedding” ACS Biomaterials Science and Engineering, 6, 1333–1343, 2020 (cover article)

183) Thavandiran N, Hale C, Blit P, Sandberg M, McElvain M, Gagliardi M, Sun B, Witty A, Graham G, Van TH Do, Bakooshli MA, Le H, Ostblom J, McEwen S, Chau E, Prowse A, Fernandes I, Gilbert PM, Keller G, Tagari P, Xu H, Radisic M, Zandstra P: “ Functional arrays of human pluripotent stem cell-derived cardiac microtissues”, Scientific Reports, 10, 1-13, 2020

182) Lu RXZ, Benge T, Lai BFL, Wang EY, Davenport Huyer L, Radisic M: “Heart-on-a-chip platform for evaluation of nanoparticle induced toxicity”, Advanced Materials Technologies, 2000726, https://doi.org/10.1002/admt.202000726, 2020

181) Sparks HD, Sigaeva T, Tarra S, Mandla S, Popel H, Heel O, DiMartino E, Biernaskie J, Radisic M. Scott WM: “Biomechanics of wound healing in an equine limb model: effect of location and treatment with a peptide-modified collagen-chitosan hydrogel”, ACS Biomaterials Science & Engineering, 7, 265-278, 2020

180) Davenport Huyer L, Mandla S, Wang Y, Yee B, Euler C, Lai BF, Bannerman D, Lin D SY, Montgomery M, Nemr K, Bender T, Epelman S, Mahadevan R, Radisic M: “Macrophage immunomodulation through new polymers that recapitulate functional effects of itaconate as a power house of innate immunity” Advanced Functional Materials, 31, 2003341, 2020

179) Lai BFL, Lu RXZ, Hu Y, Davenport Huyer L, Dou W, Wang EY, Radulovich N, Tsao MS, Sun Y, Radisic M: “Recapitulating pancreatic tumor microenvironment through synergistic use of patient organoids and organ-on-a-chip vasculature” Advanced Functional Materials, 30, 2000545, 2020

178) Kuzmanov U, Wang EY, Vanderlaan R, Guo H, Hadipour-Lakmehsari S, Zhao Y, Kim DH, Sharma P, Billia F, Radisic M, Gramolini A, Emili A: “Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources”, Nature Biomedical Engineering, 4, 9, 889-900, 2020

177) Bannerman D, Davenport Huyer L, Montgomery M, Zhao N, Velikonja C, Bender T, Radisic M: “Elastic Biomaterial Scaffold with Spatially Varying Adhesive Design” Advanced Biosystems, 4,8, 2070081, 2020 (cover article)

176) Zhang B, Radisic M; “Organ-level vascularization: The Mars mission of bioengineering” Journal of Thoracic and Cardiovascular Surgery 159, Pages 2003-2007, 2020

175) Zhao Y, Rafatian N, Wang EY, Wu Q, Lai BFL, Lu RX, Savoji H, Radisic M “ Towards chamber specific heart-on-a-chip for drug testing applications” Advanced Drug Delivery Reviews, Jan 2020 doi: 10.1016/j.addr.2019.12.002

174) Radisic M “From Engineered Tissues and Microfludics to Human Eyes-On-A-Chip” Journal of Ocular Pharmacology and Therapeutics, 36, 4-6, 2020

173) D’Costa K, Kosic M, Lam A, Moradipour A, Zhao Y, Radisic M: “Biomaterials and Culture Systems for Development of Organoid and Organ-on-a-Chip Annals of Biomedical Engineering” Annals of Biomedical Engineering, April, 1-26, 2020 https://doi.org/10.1007/s10439-020-02498-w

172) Davenport Huyer L, Pascual‐Gil S, Wang Y, Mandla S, Yee B, Radisic M: “Advanced Strategies for Modulation of the Material–Macrophage Interface” Advanced Functional Materials, April, 2020 https://doi.org/10.1002/adfm.201909331

171) Little M, Liu G-H, Shenoy KV, Vunjak-Novakovic G, Radisic M: “Engineering Tissues and Organs: The Road to the Clinic” Cell, 181, 22-23, 2020

170) Zhao Y, Eng G, Lee B, Radisic M, Vunjak-Novakovic G: ”Chapter 33: Cardiac Tissue Engineering”. Principles of Tissue Engineering, 5th Edition. Robert Lanza (Editor), Robert Langer (Editor), Joseph P. Vacanti (Editor), Anthony Atala (Editor), Academic Press, 2020, eBook ISBN: 9780128214015; Hardcover ISBN: 9780128184226; Page number 1678

169) Zhao Y, Wang EY, Davenport-Huyer L, Liao S, Yeager K, Vunjak-Novakovic G, Radisic M, Zhang B: “A multimaterial microphysiological platform enabled by rapid casting of elastic micro-wires”, Advanced Healthcare Materials, Feb 9:e1801187. doi: 10.1002/adhm.201801187, 2019 (back cover)

168) Zhao Y, Rafatian N, Feric NT, Aschar-Sobbi R, Zhang B, Wang EY, Conant G, Ronaldson K, Pahnke A, Protze S, Lee JH, Davenport-Huyer L, Jekic D, Keller GM, Vunjak-Novakovic G, Aggarwal P, Broeckel U, Backx PH, Radisic M: “A platform for generation of cardiac tissues with chamber-specific electrophysiological properties” Cell, 176:913-927, 2019 (featured article, covered by Kit Parker)

167) Zhao Y, Rafatian N, Wang EY, Feric NT, Lai BFL, Knee-Walden EJ, Backx PH, Radisic M: “Engineering microenvironment for human cardiac tissue assembly in heart-on-a-chip platform”, Matrix Biology, 85–86, 189-204, 2020

166) Wang EY, Rafatian N, Zhao Y, Lee A, Lai BF, Lu X, Jekic D, Davenport Huyer L; Walden EJ, Bhattacharya S, Backx PH, Radisic M: “Biowire model of interstitial and focal cardiac fibrosis” ACS Central Science, 5, 1146-1158, 2019 (cover paper)

165) Davenport Huyer L, Bannerman AD, Wang Y, Savoji H, Knee-Walden EJ, Brissenden A, Yee B, Shoaib M, Bobicki E, Amsden BG, Radisic M; “One-Pot Synthesis of Unsaturated Polyester Bioelastomer with Controllable Material Curing for Microscale Designs” Advanced Healthcare Materials, 2019 doi: 10.1002/adhm.20190024 (cover paper)

164) Mandla S, Davenport Huyer L, Wang Y, Radisic M: “Macrophage Polarization with Angiopoietin-1 Peptide QHREDGS” ACS Biomaterials Science and Engineering, 5, 4542-4550, 2019

163) Bannerman D, Pascual-Gil S, Radisic M; “An optimal gel patch for the injured heart” Nature Biomedical Engineering 3, 592-593, 2019 (Aug 2019)

162) Korolj A, Wu HT, Radisic M; “A healthy dose of chaos: Using fractal frameworks for engineering higher-fidelity biomedical systems” Biomaterials. 219, 119363, 2019 (Oct 2019)

161) Parrish J, Lim K, Zhang B, Radisic M, Woodfield TBF; “New Frontiers for Biofabrication and Bioreactor Design in Microphysiological System Development” Trends in Biotechnology 37, 1327-1343, 2019 (Dec 2019)

160) Savoji , Mohammadi MH, Rafatian N, Toroghi MK, Wang EY, Zhao Y, Korolj A, Ahadian S, Radisic M; “Cardiovascular disease models: A game changing paradigm in drug discovery and screening” Biomaterials,198, 3-26, 2019 (Apr 2019)

159) Radisic M; “Building a better model of the retina” Elife 8, e51183, 2019

158) Montgomery M, Davenport-Huyer L, Bannerman D, Mohammadi MH, Conant G, Radisic M: “A Method for the Fabrication of Elastomeric Polyester Photocrosslinkable Scaffolds for Tissue Engineering and Minimally Invasive Delivery”, ACS Biomaterials Science & Engineering, 2018

157) Mandla S, Davenport Huyer L, Radisic M; “Review: Multimodal bioactive material approaches for wound healing” APL Bioeng. 2018 Jun 26;2(2):021503. doi: 10.1063/1.5026773. eCollection 2018 Jun. Review.

156) Zhang B, Lai BFL, Xie R, Davenport-Huyer L, Montgomery M, Radisic M: “Microfabrication of AngioChip”, Nature Protocols, 13:1793-1813, 2018

155) Korolj A, Laschinger C, James C, Hu E, Willette R, Smith N, Ahadian A, Radisic M, Zhang B: Biomimetic 3D platform induces nephrin upregulation in differentiating podocytes in vitro “, Lab-on-a-Chip, 18:3112-3128, 2018

154) Ahadian S, Civitarese R, Bannerman D, Mohammadi MH, Lu XR, Wang E, Davenport-Huyer L, Lai F, Zhang B, Zhao Y, Mandla S, Korolj A, Radisic M: “Organ-on-a-chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies”, Advanced Healthcare Materials, 7(2). doi: 10.1002/adhm.201700506, 2018

153) Bannerman D, Lu R, Korolj A, Kim L, Radisic M: “The use of Microfabrication Technology to Address the Challenges of Building Physiologically Relevant Vasculature”, Current Opinion in Biomedical Engineering, 6: 8-16, 2018

152) Zhang JJ, Zhu W, Radisic M and Vunjak-Novakovic G: ” Can we engineer a human cardiac patch for therapy”, Circulation Research, 123:244-265, 2018

151) Mandla S, Davenport Huyer L, Radisic M: “Multimodal bioactive material approaches for wound healing” APL Bioengineering, 2(2): 1063, 2018

150) Savoji H, Mohammadi MH, Rafatian N, Toroghi MK, Wang EY, Zhao Y, Korolj A, Ahadian S, Radisic M: “Cardiovascular disease models: A game changing paradigm in drug discovery and screening”, Biomaterials, S0142-9612(18)30681-1, 2018

149)Montgomery M, Davenport-Huyer L, Bannerman D, Mohammadi MH, Conant G, Radisic M: “A Method for the Fabrication of Elastomeric Polyester Photocrosslinkable Scaffolds for Tissue Engineering and Minimally Invasive Delivery”, ACS Biomaterials Science & Engineering,10.1021/acsbiomateri, 2018

148) Zhang B, Korolj A, Lai BFL, Radisic M: “Advances in organ-on-a-chip engineering”, Nature Reviews Materials, 3: 257-278, 2018

147) Radisic M: “Biomaterials Going Strong in Canada for Half a Century”, ACS Biomaterials Science & Engineering 4: 3625-3626, 2018 (editorial)

147) Mandla S, Radisic M: “Cardiac Tissue”. Chapter in in Principles of Regenerative Medicine (Atala A., Lanza R.A., Thomson J.A., Nerem R. M. Eds.), 2^nd edition, Elsevier, 3rd edition, Elsevier ,2018 (book chapter)

146) Ahadian S, Davenport-Huyer L, Estili M, Yee B, Smith N, Xu Z, Sun Y, Radisic M. “Moldable elastomericc polyester-carbon nanotube scaffolds for cardiac tissue engineering.” Acta Biomaterialia 52:81-91, 2017

145) Montgomery M, Ahadian S, Lo Rito M, Reis LA, Davenport-Huyer L, Akbari S, Vanderlaan R, Pahnke A, Caldarone CA, Radisic M: “Flexible Shape-memory Scaffold for Minimally Invasive Delivery of Functional Tissues”. Nature Materials, 16:1038-1046, 2017 (On August 24th, 2017 this article was in the 99 percentile (ranked 845th) of the 128,306 tracked articles of a similar age in all journals in the 96 percentile (ranked 1st) of the 31 tracked articles of a similar age in Nature Materials)

144) Lai BFL, Davenport-Huyer L, Lu RXZ, Drecun S, Radisic M (co-corresponding author), Zhang B: “InVADE: Integrated Vasculature for Assessing Dynamic Events”, Advanced Functional Materials, 27:1703524, 2017

143) Conant G, Ahadian S, Zhao Y, Radisic M: “Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires”, Scientific Reports, 7:11807, 2017

142) Rashedi I, Talele N, Wang XH, Hinz B, Radisic M, Keating A: “Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells”, PLoS One, Oct 31; 12(10):e0187348. doi: 10.1371/journal.pone.0187348. ecollection, 2017

141) Williams D, Edelman ER, Radisic M, Laurencin C, Untereker D “Engagement of the Medical Technology Sector with Society”, Science Translational Medicine, 9(385). pii: eaal4359, 2017

140) Mohammad MH, Obregón R, Ahadian S, Ramón-Azcónd J, Radisic M: “Engineered muscle tissues for disease modeling and drug screening applications” Current Pharmaceutical Design, Apr 12;9(385). pii: eaal4359, 2017

139) Korolj A, Wang E, Civitarese R, Radisic M: “Biophysical stimulation for in vitro for engineering functional cardiac tissues”, Clinical Sciences, 131:1393-1404, 2017

138) Conant G, Lai B, Lu R, Korolj A, Wang E, Radisic M: “High-content assessment of cardiac function using heart-on-a-chip as drug screening model”, Stem Cell Reviews and Reports, 13:335-346, 2017

137) Zhang B, Radisic M: “Organ-on-a-Chip devices advance to the market ”, Lab-on-a-Chip, 17:2395-2420, 2017

136) Takebe T, Zhang B, Radisic M: “ Synergistic engineering: Organoids meet organs-on-a-chip “, Cell Stem Cell, 21:297-300, 2017

135) Radisic M, Alsberg E: “Tissue Engineering”, Editorial for Special Issue, ACS Biomaterials Science & Engineering, 3:1880-1883, 2017

134) Ahadian S, Radisic M: “Nanotoxicity”, Chapter in “Nanobiomaterials Science, Development and Evaluation”, edited by Mehdi Razavi, Jayakumar Rajadas and Laura Overend, Elsevier, 2017

133) Zhang B, Montgomery M, Chamberlain MD, Ogawa S, Korolj A, Pahnke A, Wells LA, Massé S, Kim J, Reis L, Momen A, Nunes SS, Wheeler AR, Nanthakumar K, Keller G, Sefton MV, Radisic M: “Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis”, Nature Materials, doi: 10.1038/nmat4570, 15:669-78, 2016 (featured in Toronto Star, CBC The National etc. Upon publication ranked in the 99 percentile (445th) of the 130,020 tracked articles of a similar age in all journals. Cover article)

132) Davenport-Huyer L, Zhang B, Korolj A, Montgomery M, Drecun S, Conant G, Zhao Y, Radisic M: “A highly elastic and moldable polyester biomaterial for cardiac tissue engineering applications”, ACS Biomaterials Science & Engineering, 2:780–788, 2016

131) Nunes SS, Feric N, Pahnke A, Miklas JW, Li M, Coles J, Gagliarde M, Keller G, Radisic M: “Human stem cell-derived cardiac model of chronic drug exposure” ACS Biomaterials Science & Engineering, DOI: 10.1021/acsbiomaterials.5b00496 April 13, 2016

130) Massé S, Magtibay K, Jackson N, Asta J, Kusha M, Zhang B, Balachandran R, Radisic M, Deno DC, Nanthakumar K: “Resolving Myocardial Activation with Novel Omnipolar Electrograms”, Circulation: Arrhythmia and Electrophysiology, 9(7):e004107, 2016

129) Xiao Y, Feric NT, Knee EJ, Gu J, Cao S, Laschinger C, Londono C, McGuigan AP, Radisic M: “Diabetic wound regeneration using peptide-modified hydrogels targeting the epithelium”, Proceedings of the National Academy of Sciences of the United States of America, 113(40):E5792-E5801, 2016

128) Feric NT, Radisic M:” Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. Advanced Drug Delivery Reviews, 96:110-134, 2016

127) Radisic M: “Editorial: Tissue engineering of the heart”, Advanced Drug Delivery Reviews, 96:1-2, 2016

126) Feric NT, Radisic M: “Strategies and Challenges to Myocardial Replacement Therapy” Stem Cells Translational Medicine, Mar 1. pii: sctm.2015-0288, 2016

125) Ogle BM, Bursac N, Domian I, Huang NF, Menasche P, Murry C, Pruitt B, Radisic M, Wu J, Wu S1, Zhang J, Zimmermann WH, Vunjak-Novakovic G: “Distilling Complexity to Advance Cardiac Tissue Engineering”, Science Translational Medicine, 8(342):342ps13, 2016

124) Radisic M: “Signals from within”, News & Views, Nature Materials, 15:596-7, 2016

123) Xiao Y, Ahadian S, Radisic M: “Biochemical and Biophysical Cues in Matrix Design for Wound Healing Applications”, Tissue Engineering Part B, Aug 19, 2016

122) Zhao Y, Korolj A, Feric N, Radisic M: “Human pluripotent stem cell-derived cardiomyocyte based models for cardiotoxicity and drug discovery” Expert Opinion On Drug Safety, 15:1455-1458, 2016

121) Reis LA, Chiu LLY, Wu J, Feric N, Lachinger C, Momen A, Li R-K, Radisic M (corresponding author): “Hydrogels with integrin binding angiopoietin 1 derived peptide QHREDGS for treatment of acute myocardial infarction”, Circulation- Heart Failure, 8:333-41, 2015

120) Hsieh A, Feric NT and Radisic M (corresponding author): “Combined hypoxia and sodium nitrite pretreatment for cardiomyocyte protection in vitro”, Biotechnology Progress, Apr, 482-492, 2015

119) Kana K, Song H, Laschinger C, Zandstra PW, Radisic M: “PI3K Phosphorylation Is Linked to Improved Electrical Excitability in an In Vitro Engineered Heart Tissue Disease Model System”, Tissue Engineering Part A, 2015 17-18, 2379-2389, 2015

118) Xiao Y, Reis L, Zhao Y, Radisic M: “ Modifications of biomaterials with immobilized growth factors or peptides for tissue engineering applications” Methods, 2S1046-2023(15)00172-3, 2015.

117) Zhang B, Montgomery M, Davenport-Huyer L, Korolj A, Radisic M.: “Platform technology for scalable assembly of instantaneously functional mosaic tissues.” Science Advances 1(7):e1500423, 2015 (featured on Vice Motherboard, The Times of India, Gizmodo, Popular Science, New Scientist, Yahoo.ca, Gizmag, The Scientist, CityNews at 6 etc)

116) Pahnke A, Conant G, Huyer LD, Zhao Y, Feric N, Radisic M.: “The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective.” Biochemical Biophysical Research Communications. Nov 26. pii: S0006-291X(15)30929-3, 2015

115) Davenport-Huyer L, Montgomery M, Zhao Y, Xiao Y, Conant G, Korolj A, and Radisic M (corresponding author): Biomaterial based cardiac tissue engineering and its applications, Biomedical Materials, 10(3):034004. doi: 10.1088/1748-6041/10/3/034004, 2015.

114) Radisic M: “Biomaterials for cardiac tissue engineering”, Biomedical Materials, doi: 10.1088/1748-6041/10/3/030301, 2015

113) Xiao Yun, Zhang B, Liu H, Miklas JW, Gagliardi M, Pahnke A, Thavandiran N, Sun Y, Simmons CA, Keller G, Radisic M (corresponding author): “Microfabricated perfusable cardiac biowire: a platform that mimics native cardiac bundle”, Lab-on-a-Chip 14:869-82, 2014 (cover article)

112) Thavandiran N, Dubois D, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande V, McGarry P, Chen CS, Nanthakumar K, Keller G, Radisic M (co-corresponding author), Zandstra PW: “Design criteria-guided formulation of pluripotent stem cell-derived cardiac microtissues”, Proceedings of the National Academy of Sciences of the United States of America 110(49):E4698-707. doi: 10.1073/pnas.1311120110 , 2013

111) Liu H, Wen J, Xiao Y, Liu J, Hopyan S, Radisic M, Simmons CA, Sun Y : “In situ mechanical characterization of the cell nucleus by atomic force microscopy”, ACS Nano, 8:3821-8, 2014

110) Miklas JW, Nunes SS, Pahnke A, Sofla A, Radisic M: “Bioreactor for modulation of cardiac microtissue phenotype by combined mechanical and electrical stimulation” Biofabrication, 6(2):024113. doi: 1 0.1088/1758-5082/6/2/024113, 2014

109) Traister A, Li M, Aafaqi S, Lu M, Arab S, Radisic M, Guido F, Sherret J, Verma S, Slorach C, Mertens L, Hui W, Hannigan G, Maynes JT, Coles JG: “Rescue of disrupted mechanotransduction as a new therapeutic strategy in human dilated cardiomyopathy” Nature Communications, Sep 11;5:4533. doi: 10.1038/ncomms5533, 2014

108) Dang LT, Feric N, Laschinger C, Chang WY, Zhang B, Wood G, Stanford WL, Radisic M(corresponding author):” A biomaterials-based approach to inhibit apoptosis of human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS”, Biomaterials, 35:7786-99, 2014

107) Feric N, Cheng C, Coh C, Yang L, Di Tizio V, Radisic M (corresponding author): “QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization”, RSC Biomaterials Science, 2, 1384-1398, 2014

106) Reis LA, Chiu LY, Feric N, Fu L, Radisic M (corresponding author): “Biomaterials in myocardial tissue engineering” Journal of Tissue Engineering and Regenerative Medicine, Jul 28. doi: 10.1002/term.1944, 2014

105) Zhao Y, Feric NT, Thavandiran N, Nunes SS and Radisic M: “The role of tissue engineering and biomaterials in cardiac regenerative medicine”, Canadian Journal of Cardiology 30:1307-22, 2014

104) Hsieh A, Feric NT, Bogojevic D, Radisic M: “Methods for cardiomyocyte isolation from heterogeneous cell populations”, Journal of Biomaterials and Tissue Engineering, 4:845-867, 2014

103) Miklas JW, Nunes SS, Zhang B, Radisic M: “Design and fabrication of biological wires” Methods Mol Biol. 1181:157-65, 2014

102) Chiu LLY, Zhang B, Xiao Y, Radisic M (corresponding author): “Cardiac Tissue Regeneration in Bioreactors”, Chapter 36 in Biomaterials and Regenerative Medicine, Editor Peter X. Ma, October 2014

101) Miklas JW, 1,2 Nunes SS, Zhang B, Radisic M (corresponding author): ”DESIGN AND FABRICATION OF BIOLOGICAL WIRES”, Chapter 14 in “Cardiac Tissue Engineering Methods and Protocols” edited by Milica Radisic and Lauren Black, Humana Press/Springer Protocols in the series “Methods in Molecular Biology”, 2014

100) Reis LA, Chiu LLY, Feric N, Fu L, Radisic M (corresponding author): “Injectable biomaterials for cardiac repair” Chapter 3, Cardiac regeneration and repair Vol II: Biomaterials and tissue engineering, pp 49-81, Editors Li R-K, Weisel RD, Woodhead Publishing , 2014

99) Pahnke A, Montgomery M, Radisic M (corresponding author): “Spatial and Electrical Factors Regulating Cardiac Regeneration and Assembly” Chapter 3 in “Biomaterials-based Cardiac Regeneration“, Ed. Marc Ruel, Springer, 2014

“Cardiac Tissue Engineering Methods and Protocols” edited by Milica Radisic and Lauren Black, Humana Press/Springer Protocols in the series “Methods in Molecular Biology”, 2014

98) Martin C, Sofla AYN, Zhang B, Nunes SS, Radisic M (corresponding author):“Fusible core molding for fabrication of branched three-dimensional perfusable microvessels for vascular tissue engineering”, International Journal of Artificial Organs, 36:159-65, 2013

97) Sofla A, Cirkovic B, Hsieh A, Miklas JW, Filipovic N, Radisic M (corresponding author): “Enrichment of live unlabelled cardiomyocytes from heterogeneous cell populations using manipulation of cell settling velocity by magnetic field”, Biomicrofluidics 7, 014110, 2013; http://dx.doi.org/10.1063/1.4791649

96) Nunes SS, Miklas JW, Xiao Y, Zhang B, Hsieh A, Thavandiran N, Jiang J, Masse S, Ggaliardi M, Laflamme MA, Nanthakumar K, Gross G, Keller G, Radisic M (corresponding author): “Biowire: a platform for maturation of human pluripotent stem cell derived cardiomyocytes”, Nature Methods 10:781-787, 2013 (On July 03^rd, 2013 the article ranked in the 98 percentile of a sample of 10,000 of the 31,524 tracked articles of a similar age in all journals and in the 95 percentile (ranked 3rd) of the 46 tracked articles of a similar age in Nature Methods)

95) Redpath CJ, Bou Khalil M, Drozdzal G, Radisic M, McBride HM: “Mitochondrial hyperfusion during oxidative stress is coupled to a dysregulation in calcium handling within a C2C12 cell model”, PLoS One 8;8(7):e69165, 2013 doi: 10.1371/journal.pone.0069165

94) Zhang B, Peticone C, Murthy S, Radisic M (corresponding author): “A standalone perfusion platform for drug testing in microvessel networks “, Biomicrofluidics 7, 044125 , 2013; http://dx.doi.org/10.1063/1.4818837

93) Miklas JW, Dallabrida SM, Reis LA, Ismail N, Rupnick M, Radisic M (corresponding author): “QHREDGS enhances tube formation, cell metabolism and cell survival of human umbilical cord endothelial cells in collagen-chitosan hydrogels” PLoS One, 8(8):e72956, 2013 doi:10.1371/journal.pone.0072956

92) Thavandiran N, Xiao Y, Nunes SS, Radisic M (corresponding author): “Topological and electrical control of cardiac differentiation and assembly” Stem Cell Research and Therapy, 4:14, 2013

91) Chiu LLY, Radisic M (corresponding author): “Cardiac tissue engineering”, Current Opinion in Chemical Engineering, 2:41-52, 2013

90) Christman KL, Radisic M (co-corresponding author): “Materials Science and Tissue Engineering: Repairing the Heart” Mayo Clinic Proceedings , 88:884-98, 2013

89) Miklas JW, Nunes SS, Radisic M (corresponding author): “Engineering cardiac tissues from pluripotent stem cells for drug screening and studies of cell maturation”, Israel Journal of Chemistry, Special Issue in Honor of Prof. Robert Langer’s Wolf Prize, 53:680–694, 2013

88) Nunes SS, Miklas JW, Radisic M (co-corresponding author): “Maturation of stem cell-derived human heart tissue by mimicking fetal heart rate”, Future Cardiology, 9:751-4, 2013

87) Bhumiratana S, Cimetta E, Tandon N, Grayson W, Radisic M, Vunjak-Novakovic G: “Tissue Engineering Bioreactors” Chapter 22, Tissue Engineering Principles and Practices, CRC Press, Edited by John P. Fisher, Antonios G. Mikos, Joseph D. Bronzino, Donald R. Peterson, 2013

86) Eng G, Lee B, Radisic M, Vunjak-Novakovic G: ”Cardiac Tissue Engineering”. Principles of Tissue Engineering, 4th Edition Robert Lanza (Editor), Robert Langer (Editor), Joseph P. Vacanti (Editor), Academic Press, June 15^th, 2013

85) Reis LA, Chiu LL, Liang Y, Hyunh K, Momen A, Radisic M (corresponding author): “Apeptide-modified chitosan-collagen hydrogel for cardiac cell culture and delivery”, Acta Biomaterialia, 8:1022-36, 2012

84) Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS: “A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues”, Tissue Engineering Part A. (9-10):910-9, 2012

83) Chiu LLY, Janic K, Radisic M (corresponding author): “Engineering of oriented myocardium on three-dimensional micropatterned collagen-chitosan hydrogel”, International Journal of Artificial Organs, 35:237-250, 2012

82) Iyer RK, Odedra D, Vunjak-Novakovic G, Radisic M (corresponding author): “VEGF Secretion by Non-Myocytes Modulates Connexin-43 Levels in Cardiac Organoids”, Tissue Engineering Part A, 18:1771-83, 2012

81) Zhang B, Green JV, Murthy SK, Radisic M (corresponding author): “Label-free enrichment of functional cardiomyocytes using microfluidic deterministic lateral flow displacement”, PLoS One 2012;7(5):e37619. Epub 2012 May 29.

80) Leng L, McAllister A, Zhang B, Radisic M, Günther A: “Mosaic hydrogels: One-step formation of multidimensional, multiscale soft materials”, Advanced Materials, 24:3650-8, 2012 (cover article)

79) Al-Haque S, Miklas J, Feric N, Chiu LLY, Chen WLK, Simmons CA, Radisic M (corresponding author): “Substrate stiffness and topography simultaneously influence cardiac fibroblast contact guidance on hydrogels “, Macromolecular Bioscience, 12:1342-53, 2012 (cover article)

78) Iyer TK, Chiu LLY, Vunjak-Novakovic G, Radisic M (corresponding author): “Sequential Preculture of Non-Myocytes Improves Formation of Vascular-Like Cords in Engineered Cardiac Tissues”, Biofabrication 4:035002, 2012

77) Chiu LLY, Reis LA, Momen A, Radisic M (corresponding author): “Controlled release of thymosin β4from injected collagen-chitosan hydrogels promotes angiogenesis after myocardial infarction in rats”, Regenerative Medicine, 7:523-33, 2012

76) Kang K, Sun L, Xiao Y, Li S-H, Wu Y, Yau TM, Weisel RD, Radisic M, Li R-K : “Aged Human Cells Rejuvenated by Cytokine-Enhancement of Biomaterials for Surgical Ventricular Restoration”, Journal of the American College of Cardiology, 20:2237-49, 2012

75) Chiu LLY, Montgomery M, Liang Y, Liu H, Radisic M (corresponding author): “Perfusable branching microvessel bed for vascularization of engineered tissues”, Proceedings of the National Academy of Sciences of the United States of America, 109:E3414-23, 2012

74) Chiu LL, . Iyer RK, Reis LA, Nunes SS, Radisic M (corresponding author): “Cardiac Tissue Engineering: Current State and Perspectives” Frontiers in Bioscience,17:1533-50, 2012

73) Chiu LLY, Reis L, Radisic M (corresponding author): ”Controlled Delivery of Thymosin β4 for Tissue Engineering and Cardiac Regenerative Medicine” Annals of the New York Academy of Sciences, 69:16-25, 2012

72) Tandon V, Zhang B, Radisic M, Murthy SK: “Generation of Tissue Constructs for Cardiovascular Regenerative Medicine: From Cell Procurement to Scaffold Design” Biotechnology Advances 2012 Aug 24. doi:pii: S0734-9750(12)00145-0. 10.1016/j.biotechadv.2012.08.006. [Epub ahead of print] (NIH only)

71) Xiao Y, Zhang B, Hiesh A, Thavandiran N, Marin C, Radisic M (corresponding author): “Microfluidic Cell Culture Techniques” Microfluidic Cell Culture Systems, 2nd Edition, Editors Bettinger CJ, Borenstein JT, Tao SL, Elsevier, pp 303-316, December 28^th, 2012

70) Chiu LLY, Weisel RD, Li R-K, Radisic M (co-corresponding author): “Defining conditions for covalent immobilization of angiogenic growth factors onto scaffolds for tissue engineering”, Journal of Tissue Engineering and Regenerative Medicine, 5:69-84, 2011

69) Rask F, Mihic A, Reis L, Dallabrida SM, Ismail NS, Sider K, Simmons CA, Rupnick MA, Weisel RD, Li R-K, Radisic M (corresponding author): “Hydrogels modified with QHREDGS peptide support heart cell survival in vitro and after sub-cutaneous implantation”, Soft Matter, 6:5089-5099, 2010

68) Dengler J, Song H, Massé S, Wood G, Nanthakumar K, Zandstra PW and Radisic M (corresponding author): “An in vitro model system for cardiac stem cell therapy”, Biotechnology & Bioengineering ,108: 704-719, 2011

67) Miyagi Y and Chiu LLY, Cimini M, Weisel RD, Radisic M (co-corresponding author), Li R-K “Biodegradable collagen patch with covalently immobilized VEGF improves right ventricular repair”, Biomaterials, 32:1280-90, 2011

66) Song H, Zandstra P, Radisic M (corresponding author): “Engineered heart tissue model of diabetic myocardium.”, Tissue Engineering, (13-14):1869-78, 2011

65) Odedra D, Shoichet M, Radisic M (co-corresponding author): “Endothelial Cells Guided by ImmobilizedGradients of Vascular Endothelial Growth Factor on Porous Collagen Scaffolds”, Acta Biomaterialia,7:3027-35, 2011

64) Chiu LLY, Iyer RK, Radisic M (corresponding author): “Biphasic electrical field stimulation aids in tissue engineering of multi-cell type cardiac organoids”, Tissue Engineering Part A, 17:1465-77, 2011

63) Chiu LLY, Radisic M (corresponding author): “Controlled release of thymosin β4 using collagen-chitosan composite hydrogels promotes epicardial cell migration and angiogenesis”, Journal of Controlled Release, 155:376-85, 2011

62) Iyer RK, Chiu LLY, Reis L, Radisic M (corresponding author): “Engineered Heart Tissue” Current Opinion in Biotechnology, 22:706-14, 2011

61) Nunes SS, Song H, Chiang K, Radisic M (co-corresponding author): “Stem cell-based cardiac tissue engineering”, Journal of Cardiovascular Translational Research, 4:592-602, 2011

60) Zhang B, Xiao Y, Hsieh A, Thavandiran N, Radisic M (corresponding author): “ Micro and nanotechnology in cardiovascular tissue engineering”, Nanotechnology, 22(49):494-503, 2011

59) Radisic M, Sefton MV: “Cardiac Tissue” Chapter 48 in Principles of Regenerative Medicine (Atala A., Lanza R.A., Thomson J.A., Nerem R. M. Eds.), 2^nd edition, Elsevier, pp877-909, 2011

58) Odedra D, Chiu K, Reis K, Rask F, Chiang K, Radisic M (corresponding author): Chapter 15, “Cardiac Tissue Engineering” in “Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends” Editors Jason Burdick and Robert Mauck, Springer-Verlag, pp 421-456, 2011

57) Chiu LLY, Radisic M (corresponding author): “Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues”, Biomaterials, 31:226-241, 2010

56) Song H, Yoon C, Kattaman SJ, Dengler J, Thavaratnam T, Gewarges M, Masse S, Nanthakumar K, Rubart M, Keller GM, Radisic M (co-corresponding author), Zandstra P: “Interrogating functional integration between injected pluripotent stem cell derived-cells and surrogate cardiac tissue”, Proceedings of the National Academy of Sciences of the United States of America, 107:3329-3334, 2010

55) Chiang K, Chowdhury MF, Iyer RK, Stanford WL, Radisic M (co-corresponding author): “Engineering surfaces for site specific vascular differentiation of mouse embryonic stem cells”, Acta Biomaterialia, 6:1904-16, 2010

54) Rask F, Dallabrida SM, Ismail NS, Amoozgar Z, Yeo Y, Rupnick M, Radisic M. (corresponding author):“Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells”, Journal of Biomedical Materials Research Part A, 95:105-117, 2010

53) Vunjak-Novakovic G, Tandon N, Godier A, Maidhof R, Marsano A, Martens T, Radisic M: “Challenges in Cardiac Tissue Engineering” Tissue Engineering Part B, 16:169-187, 2010

52) Chiu LLY, Radisic M (co-corresponding author), Vunjak-Novakovic G: “Biomaterials for engineering vascularized cardiac tissues”, Macromolecular Bioscience, 10:1286-301, 2010 (Frontispiece)

51) Chiu LLY, Chu Z, Radisic M (corresponding author) :”Tissue Engineering” Volume 2, Chapter 7 in Comprehensive Nanoscience and Technology (Editors in Chief David Andrews, Greg Scholes, Gary Wiederrecht; Vol4 Editors. Rienk van Grondelle, Brent Krueger, Gilbert Walker), Elsevier, Vol.2, pp 175-211, 2010

50) Bhana B and Iyer RK, Chen WLK, Zhao R, Sider KL, Simmons CA, Radisic M (corresponding author):“Influence of Substrate Stiffness on the Phenotype of Heart Cells”, Biotechnology & Bioengineering, 105:1148-1160, 2010 (cover in June 2011)

49) Iyer RK, Chiu L, Radisic M (corresponding author): “Microfabricated poly(ethylene glycol) templates enable rapid screening of tri-culture conditions for cardiac tissue engineering”, Journal of Biomedical Materials Research Part A, 89A:616-31, 2009

48) Radisic M (co-corresponding author), Fast VG, Sharifov OF, Iyer RK, Park H, Vunjak-Novakovic G: “Optical mapping of impulse propagation in engineered cardiac tissue”, Tissue Engineering Part A, 15:851-60, 2009

47) Tandon N, Cannizzaro C, Chao PH, Maidhof R, Marsano A, Au HT, Radisic M, Vunjak-Novakovic G.“Electrical stimulation systems for cardiac tissue engineering”, Nature Protocols, 4:155-173, 2009

46) Heidi Au HT, Cui B, Chu ZE, Veres T, Radisic M. (co-corresponding author): “Cell culture chips forsimultaneous application of topographical and electrical cues enhance phenotype of cardiomyocytes” , Lab-on-a-Chip, 9:564-575, 2009

45) lyer RK, Chui J, Radisic M. (corresponding author): “Spatiotemporal tracking of cells in tissue-engineered cardiac organoids.”, Journal of Tissue Engineering and Regenerative Medicine, 3:196-207, 2009

44) Plouffe BD, Brown MA, Iyer RK, Radisic M (co-corresponding author), Murthy SK: “Controlled Captureand Release of Cardiac Fibroblasts using Peptide-Functionalized Alginate Gels in MicrofluidicChannels”, Lab- on -a -Chip, 9:1507-10, 2009

43) Green JV, Radisic M, Murthy SK: “Deterministic Lateral Displacement as a Means to Enrich Large Cells for Tissue Engineering”, Analytical Chemistry, 81:9178-9182, 2009

42) Grayson WL, Martens TP, Eng GM, Radisic M, Vunjak-Novakovic G: “Biomimetic approach to tissue engineering” Seminars in Cell & Developmental Biology, 20:665-73, 2009

41) Eng G, Radisic M, Vunjak-Novakovic G: “Controlling the cellular microenvironment” Chapter 10 in Microdevices in Biology and Medicine (Ed. Nhamias Y, Bhatia S) Artech House, pp211-234, 2009

40) Radisic M, Park H, Salazar-Lazaro JE, Wang Y, Langer R, Freed LE, Vunjak-Novakovic G: “Pretreatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue”, Journal of Biomedical Materials Research Part A, 86:713-724, 2008

39) Wallis MC, Yeger H, Cartwright L, Shou Z, Radisic M, Haig J, Suoub M, Farhat WA: “Feasibility studybof a novel urinary bladder bioreactor” Tissue Engineering,14:339-348, 2008

38) Radisic M, Marsano A, Maidhof R, Wang Y, Vunjak-Novakovic G. “Cardiac tissue engineering using perfusion bioreactor systems” , Nature Protocols, 3:719-38, 2008

37)Plouffe BD, Radisic M, Murthy SK: “Microfluidic Depletion of Endothelial Cells, Smooth Muscle Cells, and Fibroblasts from Heterogeneous Suspensions”, Lab-on-a-Chip, 3:462-472, 2008

36) Shen Y-H, Shoichet M, Radisic M (corresponding author): “Vascular endothelial growth factorimmobilized in collagen scaffold promotes proliferation and penetration of endothelial cells”, Acta Biomaterialia, 4:477-489, 2008

Brown MA, Iyer RK, Radisic M (corresponding author): “Pulsatile perfusion bioreactor for cardiac tissue engineering”, Biotechnology Progress, 24:907-920, 2008

Park H, Bhalla R, Saigal R, Radisic M, Watson N, Langer R, Vunjak-Novakovic G. “Effects of electrical stimulation in C2C12 muscle constructs”, Journal of Tissue Engineering and Regenerative Medicine 2:279-287, 2008

35) Radisic M, Sefton MV: “Cardiac Tissue” Chapter 60 in Principles of Regenerative Medicine (Atala A., Lanza R.A., Thomson J.A., Nerem R. M. Eds.) Elsevier, pp1038-1059, 2008

34) Grayson W, Chao Ph-G, Marolt D, Radisic M, Cannizzaro C, Figallo E, Vunjak-Novakovic G: “Bioreactors for tissue engineering and regenerative medicine” Chapter 20 in Translational Approaches in Tissue Engineering and Regenerative Medicine (Eds: Jeremy Mao, Gordana Vunjak-Novakovic, Antonios Mikos, Anthony Atala) Artech House, 2008

33) Malda J, Radisic M, Levenberg S, Woodfield T, Oomens C, Baaijens C, Svalander P, Vunjak-Novakovic G: “Cell Nutrition” Chapter 12 in Tissue Engineering (Ed. Clemens van Blitterswijk) Academic Press Series in Biomedical Engineering, pp 327-363 Apr 08^th, 2008

32) Iyer RK, Plouffe B, Murthy SK, Radisic M (corresponding author): “Microreactors for cardiac tissue engineering” for Micro- and Nanoengineering of the Cell Microenvironment: Technologies and Applications Artech House, pp 361-389, (Eds. Ali Khademhosseini, Jeffrey Borenstein, Shuichi Takayama, Mehmet Toner), 2008

31) Murthy SK and Radisic M: “Cell Adhesion and Detachment” Encyclopedia of Micro- and Nanofluidics” (Ed. Li, Dongqing) Springer-Verlag, pp202-208, 2008

30) Murthy SK, Sethu P, Vunjak-Novakovic G, Toner M, Radisic M (corresponding author): “Size-Based Microfluidic Enrichment of Neonatal Rat Cardiac Cell Populations”, Biomedical Microdevices, 8:231-237, 2007

29) Plouffe BD, Njoka D, Harris J, Liao J, Horick NK, Radisic M, Murthy SK: “Peptide-Mediated Selective Adhesion of Smooth Muscle and Endothelial Cells in Microfluidic Shear Flow”, Langmuir, 23:5050-5055, 2007

28) Khademhosseini A, Eng G, Yeh J, Kucharczyk PA, Langer R, Vunjak-Novakovic G, Radisic M (corresponding author): “Microfluidic patterning for fabrication of contractile cardiac organoids”, Biomedical Microdevices, 9:149-157, 2007

27) Au HTH, Cheng I, Chowdhury MF, Radisic M “Interactive effects of surface topography and pulsatile electrical field stimulation on fibroblasts and cardiomyocytes”, Biomaterials, 28: 4277-93, 2007

26) Iyer RK, Radisic M, Cannizzaro C, Vunjak-Novakovic G: “Synthetic Oxygen Carriers in cardiac Tissue Engineering” Artificial Cells Blood Substitutes and Immobilization Biotechnology, 35:135-48, 2007

25) Radisic M, Park H, Gerecht-Nir S, Cannizzaro C, Freed LE, Langer R, Vunjak-Novakovic G: “Biomimetic Approach to Cardiac Tissue Engineering” Philosophical Transactions of the Royal Society –B, 362: 1357-68, 2007 (Issue: Bioengineering the Heart, August 2007)

24) Dengler J and Radisic M (corresponding author): “Tissue engineering approaches for development of a contractile cardiac patch” Future Cardiology, 3:425-434, 2007

23) Obradovic B, Radisic M, Vunjak-Novakovic G: “Oxygen Transport in Tissue Engineering Systems: Cartilage and Myocardium” Fluid Dynamics and Materials Processing, 3:189-202, 2007

22) Radisic M, Park H, Vunjak-Novakovic G: “Cardiac-Tissue Engineering” Principles of Tissue Engineering 3rd Ed. (Lanza R, Langer R, Vacanti, eds) Elsevier; Chpt 38, pp. 551-549, 2007

21) Cannizzaro C, Tandon N, Figallo E, Park H, Gerecht S, Radisic M, Elvassore N,Vunjak-Novakovic G: “Practical aspects of cardiac tissue engineering with electrical stimulation” Methods in Molecular Medicine – Tissue Engineering 2nd Edition, (Martin Fussenegger, Hansjoerg Hauser Eds) Humana Press , 140:291-307, 2007

20) Radisic M , Malda J, Epping E, Geng W, Langer R, Vunjak-Novakovic G: “Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue”, Biotechnology & Bioengineering, 93:332-343, 2006

19) Radisic M , Park H, Chen F, Wang Y, Dennis R, Langer R, Freed LE, Vunjak-Novakovic G: “Biomimetic approach to cardiac tissue engineering: Oxygen carriers in channeled scaffolds”, Tissue Engineering, 12: 2077-91, 2006 (Cover article)

18) Karp JM, Yeo Y, Geng W, Cannizarro C, Jan K, Kohane DS, Vunjak-Novakoviv G, Langer RS, Radisic M (corresponding author): “A Photolitographic Method to Create Cellular Micropatterns”, Biomaterials 27:4755-64, 2006

17) Yeo Y, Geng, W, Ito T, Kohane DS, Burdick JA, Radisic M (corresponding author): “A photocrosslinkable hydrogel for myocyte cell culture and injection”, Journal of Biomedical Materials Research Part B, 81:312-322, 2006

16) Vunjak-Novakovic G, Radisic M, Obradovic B: “Cardiac tissue engineering: effects of bioreactor flow environment on tissue constructs” Journal of Chemical Technology and Biotechnology, 81:485-490, 2006

15) Gerecht-Nir S, Radisic M, Park H, Cannizzaro C, Boublik J, Langer R, et al.: “Biophysical regulation during cardiac development and application to tissue engineering” International Journal of Developmental Biology, 50:233-243, 2006

14) Radisic M (co-corresponding author), Iyer RK, Murthy SK: “Micro- and Nano- Technology in Cell Separation” International Journal of Nanomedicine, 1:3-14, 2006

13) Radisic M, Cannizzaro C, Vunjak-Novakovic G: “Scaffolds and fluid flow in cardiac tissue engineering” Fluid Dynamics and Materials Processing, 2:1-16, 2006

12) Freed LE, Guilak F, Guo XE, Gray ML, Tranquillo R, Holmes JW, Radisic M, Sefton MV, Kaplan D, Vunjak-Novakovic G: “Advanced Tools for Tissue Engineering: Scaffolds, Bioreactors, and Signalling” Tissue Engineering , 12: 3285-3305, 2006

11) Radisic M , Deen WM, Langer R, Vunjak-Novakovic G: “Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers”, American Journal of Physiology-Heart and Circulatory Physiology, 288: H1278-H1289, 2005

10) Boublik J, Park H, Radisic M, Tognana E, Chen F, Pei M, Vunjak-Novakovic G, Freed LE: “Mechanical function and remodeling of hybrid cardiac constructs made from heart cells, fibrin, and a biodegradable, elastomeric knitted fabric”, Tissue Engineering, 11: 1122-1132, 2005

9) Park H, Radisic M, Lim JO, Chung BH, Vunjak-Novakovic G: “A novel composite scaffold for cardiac tissue engineering”, In Vitro Cell and Developmental Biology-Animal,41:188-196, 2005

8) Radisic M and Vunjak-Novakovic G: “Cardiac Tissue Engineering” Journal of the Serbian Chemical Society, 70:541-556, 2005

7) Obradovic B, Radisic M, Vunjak-Novakovic G: “Functional tissue engineering of cartilage and myocardium” In: Focus on Biotechnology, Volume 8b: Applications of Cell Immobilisation Biotechnology, (V. Nedovic and R.G.Willaert, eds.), Springer Dordrecht, Berlin, Heidelberg, New York, pp. 99-133, 2005.

6) Radisic M, Obradovic B, Vunjak-Novakovic G: “Bioreactor Designs in Tissue Engineering” in Scaffolding in Tissue Engineering (J. Elisseef and P.X. Ma, eds), Taylor &Francis CRC Press Chpt 33, pp. 491-520 , 2005.

5) Radisic M , Yang L, Boublik J, Langer R, Freed LE, Vunjak-Novakovic G: “Medium perfusion enables cultivation of compact and contractile cardiac tissue”, American Journal of Physiology-Heart and Circulatory Physiology 286: H507-516, 2004

4) Radisic M , Park H, Shin H, Consi T, Schoen FJ, Freed LE, Vunjak-Novakovic G: “Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds”, Proceedings of the National Academy of Sciences of the United States of America, 101:18129-18134, Dec 28, 2004 (Cover article)

3) Vunjak-Novakovic G and Radisic M: “Cell Seeding of Polymer Scaffolds”, Chapter 11 in Methods in Molecular Biology/Biotechnology/Medicine Series: Biopolymer Methods in Tissue Engineering (A. Hollander, P. Hatton, eds.) Humana Press, vol. 238: 131-145 2004

2) Rodic M, (maiden name) and Hrymak AN: “The modified disc retraction method for measurement of interfacial tension in polymer melts”, Rheologica Acta, 40:339-349, 2003

1) Radisic M , Euloth M, Yang L, Langer R, Freed LE, Vunjak-Novakovic G: “High density seeding of myocyte cells for cardiac tissue engineering”, Biotechnology & Bioengineering 82: 403-414, 2003